Programme


PERINATAL MEDICINE 2014
PROGRAMME


MONDAY 9th JUNE 2014


11.30 – 13.00 Registration  

 

   
SESSION 1 SOCIETY LECTURES PLENARY
     
13.00 – 13.45 THE BRITISH ASSOCIATION OF PERINATAL MEDICINE: FOUNDERS LECTURE  
     
  The intestinal microbiome, inflammation, and neonatal morbidity
Professor Josef Neu MD, Professor of Paediatrics, University of Florida, USA
 
     
13.45 – 14.30 BRITISH MATERNAL & FETAL MEDICINE SOCIETY: SOCIETY LECTURE  
     
  Noninvasive prenatal diagnosis in routine clinical care: The opportunities, risks and the changing face of our subspecialty
Professor Lyn Chitty, Professor of Genetics and Fetal Medicine, Institute of Child Health UCL, London 
 
     
14.30 – 15.15 Tea, Exhibition, Poster Viewing  
     
SESSION 2  Fetal Medicine  
     
15.15 – 16.05 Free Papers  
     
2.1

Estimation of detection rates of aneuploidy using an approach based on nuchal translucency and non-invasive prenatal testing (NIPT)

A Khalil, N Mahmoodian, A Kulkarni, T Homfray, A Papageorghiou, A Bhide, B Thilaganathan  London UK

 
     
2.2

Abnormal cerebroplacental ratio predicts adverse outcomes in dichorionic twins

EM Kent, FM Breathnach, G Burke, FM McAuliffe, MP Geary, S Daly, JR Higgins, A Hunter, JJ Morrison, S Higgens, R Mahony, P Dicker, EC Tully,  FD Malone, Dublin Ireland

 
     
2.3

Exome sequencing improves genetic diagnosis of structural fetal abnormalities revealed by ultrasound

SC Hillman, K Carss, D McMullen, V Parthiban, E Maher, M Kilby, M Hurles, Birmingham UK

 
     
2.4

Whole exome sequencing of growth restricted offspring identifies gene variants implicated in maturity onset diabetes of the young

SL Hillman, MC Smart, C Bacchelli, L Ocaka, DJ Williams, London UK

 
     
2.5

Direct fetal DNA Fraction Enrichment using microfluidic sample presentation of maternal blood for Non-Invasive prenatal testing

M Kersaudy-Kerhoas, MPY Desmulliez, J Norman, Edinburgh UK

 
16.10 – 16.40 The role of fetal MRI as an imaging modality of brain abnormalities
Professor Paul Griffiths
Professor of Radiology, Royal Hallamshire Hospital, Sheffield
 
     
SESSION 3 THE TIZARD LECTURE PLENARY
     
16.45 – 17.45 The potential life-long implications of neonatal hyper and hypoglycaemia
Professor Andrew Hattersley
Professor of Molecular Medicine, Exeter Medical School
 
     
17.45 – 18.45 Welcome Reception  

 


TUESDAY 10th JUNE 2014


08.00 – 08.30 Registration  
     
SESSION 4   PLENARY
     
08.30 – 09.10 The phenotype of the young adult born preterm
Professor Neena Modi
Professor of Neonatal Medicine, Imperial College London
 
     
09.10 – 09.50 Free Papers – HOT TOPICS  
     
4.1

Hyperalimentation and blood glucose control in very preterm infants: a randomised controlled parenteral nutrition study

C Morgan, L Burgess, M Grosdenier, J Green, P McGowan, MA Turner, Liverpool UK

 
     
4.2

Infant neurodevelopmental outcomes following late and moderately preterm birth

EM Boyle, ES Draper, TA Evans, DJ Field, B Manktelow, N Marlow, S Seaton, LK Smith, S Johnson, Leicester, UK

 
     
4.3

EPICure 2: Impact of antenatal steroid, tocolysis and caesarean delivery on condition at birth in extremely preterm babies

AS Morgan, ES Draper, K Bennett, Z Alfirevic, KL Costeloe, N Marlow, London UK

 
     
09.50 – 10.20 NEONATAL SOCIETY: YOUNG INVESTIGATOR PRESENTATION  
     
4.4

Winner – Dr Christopher Gale

Influencing long-term health through infant nutrition 

 
     
10.20 – 10.50 Coffee, Exhibition and Poster Viewing  

 

 

SESSION 5                                                                             PARALLEL SESSIONS

 

 

10.50 – 12.20

 

 

SESSION 5A

BRITISH MATERNAL & FETAL MEDICINE SOCIETY – MATERNAL MEDICINE

 

SESSION 5B

BRITISH ASSOCIATION OF PERINATAL MEDICINE

& NEONATAL SOCIETY


SESSION 5A BRITISH MATERNAL & FETAL MEDICINE SOCIETY – MATERNAL MEDICINE  
     
10.50 – 11.20 Maternal obesity: The maternal and fetal effects: can we intervene prenatally?
Professor Fionnula McAuliffe, Professor of Maternal & Fetal Medicine
The National Maternity Hospital, Dublin, Ireland
 
     
11.20 – 12.20 Free Papers  
     
5.1

Ruptured membranes and risk of vertical transmission in women with HIV

K Harding, C Townsend, H Peters, A De Ruiter, K Francis, G Taylor, P Tookey, London UK

 
     
5.2

The effect of morbid obesity on thrombin generation and sensitivity to the anticoagulant activated protein C in pregnant women

HD O’Connor, B Kevane, S Cooley, K Egan, K Flood, F Ni Ainle, Dublin Ireland

 
     
5.3

Postnatal testing for persistence of abnormal glucose metabolism after Gestational Diabetes: Fasting plasma glucose or oral glucose tolerance test?

N L Mudalidge, L Thornhill, S Sinha, C Cotzias, A Dixit Isleworth UK

 
     
5.4

First trimester Angiotensinogen: Kallikrein ratio is raised in women who develop severe early-onset pre-eclampsia

E Breslin, S Slade, R Akolekar, K Nicolaides, J Scrivens, S Quenby, Warwick UK

 
     
5.5

Successful insilico discovery of novel hypoxia regulated genes in pre-eclampsia

VL Karanam, N Anim-Nyame, NM Page, London & Mansfield, UK
 
     
5.6

The control of hypertension in pregnancy study (CHIPS) randomized controlled trial

LA Magee, P von Dadelszen, E Rey, S Ross, E Asztalos, K Murphy, JM Menzies, J Sanchez, J Singer, A Gafni, A Gruslin, E Hutton, SK Lee, AG Logan, JW Ganzevoort, R Welch (Derriford Hospital), JG Thornton, Vancouver Canada

 
     
SESSION 5B BRITISH ASSOCIATION OF PERINATAL MEDICINE & NEONATAL SOCIETY  
     
10.50 – 11.50 Free Papers  
     
5.7

Hyperalimentation and electrolyte requirements in very preterm infants: a randomized controlled parenteral nutrition study        

J Green, P McGowan, C Morgan, Liverpool UK

 
     
 5.8 Clinical and genetic influences on functional brain networks in preterm infants

APR Smith-Collins, A Heep, RA Kauppinen, A Varadi, S Rajatileka, E Molnar, K Luyt, Bristol UK

 
     
5.9

Behavioral, social and emotional outcomes following late and moderately preterm birth

S Johnson, ES Draper, TA Evans, DJ Field, A Guy, N Marlow, LS Seaton, ELK Smith, EM Boyle, Leicester UK

 
     
5.10

Using detailed clinical nutritional data to predict optimal energy and protein intakes for preterm infant

MJ Johnson, JP Pond, F Pearson, A Emm, AA Leaf, Southampton UK

 
     
11.50 – 12.20 Haematological insights from Downs Syndrome
Professor Irene Roberts, Professor of Paediatric Haematology, Imperial College London
 
     
12.20 – 13.40 Lunch, Exhibition and Poster Viewing  
     
SESSION 6    

                                

 

SESSION 6                                                                             PARALLEL SESSIONS

 

 

13.40 – 15.10

 

SESSION 6A

BRITISH MATERNAL & FETAL MEDICINE SOCIETY LABOUR & DELIVERY

 

SESSION 6B

BRITISH ASSOCIATION OF PERINATAL MEDICINE

& NEONATAL SOCIETY

 

 

SESSION 6A BRITISH MATERNAL & FETAL MEDICINE SOCIETY – LABOUR & DELIVERY  
     
13.40 – 14.40 Free Papers  
     
6.1

Experimental evaluation of a new device and estimation of forces applied to the impacted head at CS

GSJ Tydeman, A Briley, A Sheenan, P Seed, Kirkcaldy, UK

 
     
6.2

Atosiban activates NF-kB and pro-inflammatory pathways in human amnion via Gai signalin

V TerzidouSH Kim, A Blanks, S Thornton, PR Bennett, London UK

 
     
6.3

The commonalities and differences in the molecular expression of different phenotype-specific causes of preterm labour in comparison to term labour

N Singh, A Yuiia, V Terzidou, SR Sooranna, MR Johnson, London UK

 
     
6.4

Transfusion management and haemostatic changes in major obstetric haemorrhage in the UK

M Knight, L Green, FM Seeney, PW Collins, RE Collis, CL Hopkinson, SJ Stanworth, Oxford UK

 
     
6.5

Long-term childhood outcomes following caesarean section: systematic review and meta-analysis

OE Keag, SJ Stock, JE Norman, Edinburgh UK

 
     
6.6

Vaginal birth after caesarean section (VBAC) predictor models: Which is the best model and can it save money?

F Mone, C Harrity, B Toner, A Mackie, A Currie, T McCormick, F McAuliffe, Dublin Ireland & Craigavon UK

 
     
14.40 – 15.10 Timing of delivery in twin pregnancies
Professor Basky Thilaganathan, Professor in Maternal & Fetal Medicine
St Georges Hospital, London
 
     
SESSION 6B BRITISH ASSOCIATION OF PERINATAL MEDICINE & NEONATAL SOCIETY SESSION  
     
13.40 – 14.10 What next for NICE?
Professor David Haslam
Chair, National Institute for Health and Care Excellence
 
     
14.10 – 15.10 Free Papers  
     
6.7

Neonatal thyroid function and the use of povidone-iodine and iodinated contrast media during labour and the postnatal period: a pilot study

FLR Williams, E Velten, C Day, A Soe, S Somisetty, Dundee UK

 
     
6.8

Hepatic IGF1 DNA methylation and mrna expression are influenced by gender but not by prenatal growth restriction in the young lamb

DJ Carr, JS Milne, RP Aitken, JM Wallace, Aberdeen UK

 
     
6.9

Up-regulation and shift in cellular and tissue localisation of Epidermal Growth Factor Receptor in Acute Necrotising Enterocolitis

D Vieten, AP Corfield, RD Spicer, Bristol UK

 
     
6.10

A quality improvement initiative for reducing late onset infection among very low birth weight infants

CL Smith, JC Becher, J Orme, Y Freer, C Abbott-Smith, E Johnston, BJ Stenson, JP Boardman, Edinburgh UK

 
     
15.10 – 15.40 Tea, Exhibition and Poster Viewing  
     
SESSION 7 SGA INFANT PLENARY
     
15.40 – 16.20

Perinatal trajectories towards Obesity, Polycystic Ovary Syndrome and the World Cup                                                                                          

Professor Francis de Zegher                 

University of Leuven, Belgium

 
     
16.20 – 17.00

BRITISH ASSOCIATION OF PERINATAL MEDICINE: THE PETER DUNN LECTURE

Prenatal investigation and management of the small for gestational age baby
Professor Steve Robson, Professor in Maternal & Fetal Medicine
Royal Victoria Infirmary, Newcastle upon Tyne

 
   
 17.00 – 18.00

 AGM for BRITISH MATERNAL & FETAL MEDICINE SOCIETY

Click here for the AGM Agenda

 
 
 17.15  18.15

SPONSORED SYMPOSIUM - Medela UK

Human Milk in the NICU - latest research and process improvements aimed at improving the does of human milk to the preterm infant and increase the rate of breastfeeding

Queens Suite - Meeting Room B
 
     
19.30 – 23.00 Conference Reception and Dinner
Royal Hall, Harrogate
 
     
     

WEDNESDAY 11th JUNE 2014


08.30 – 09.00 Registration  

 

 

SESSION 8                                                                             PARALLEL SESSIONS

 

 

09.00 – 10.30

 

SESSION 8A

BRITISH MATERNAL & FETAL MEDICINE SOCIETY-PREGNANCY OUTCOME

 

SESSION 8B

BRITISH ASSOCIATION OF PERINATAL MEDICINE

& NEONATAL SOCIETY

 

SESSION 8A BRITISH MATERNAL & FETAL MEDICINE SOCIETY – PREGNANCY OUTCOME  
     
09.00 – 09.30 The role of prenatal programming and epigenetics on long-term childhood outcomes
Professor Stephen Matthews
Department of Physiology, University of Toronto, Ontario, Canada
 
     
09.30 – 10.30 Free Papers  
     
8.1

The association of maternal characteristics and macronutrient intake in pregnancy with neonatal body composition

MK Horan, CA McGowan, J Donnelly, E Gibney, FM McAuliffe, Dublin Ireland

 
     
8.2

Cardiac Ion Channelopathies in unexplained stillbirths

S Addison, PB Munroe, C Mein, M Cohen, D Fowler, NJ Sebire, D Pebbles, AM Taylor, D Abrams, S Thayyi, London UK

 
     
8.3

Placental growth factor (plgf) and ultrasound parameters for predicting the small for gestational age infant (sga) in suspected small for gestational age: pelican for study

MJ Griffin, PT Seed, LM Webster, H Tarft, LC Chappell, AH Shennan, London UK

 
     
8.4

Serum beta defensin concentration in the first trimester is related to genotype, and is higher in women who develop PPROM and deliver before 34 weeks

CP James, M Bajaj-Elliott, A Syngelaki, N Klein, K Nicolaides, DM Pebbles, London UK

 
     
8.5

Combined fetal fibronectin and saliva progesterone measurement for prediction of spontaneous preterm birth

J Carter, N Hezelgrave, P Seed, R Tribe, A David, G Lachelin, A Shennan, L Poston, London UK

 
     
8.6

The evolution of the vaginal microbiome throughout umcomplicated pregnancy in a UK population

M Chandiramani, YS Lee, L Kindinger, S Arulkumaran, J Marchesi, E Holmes, J Nicholson, TJ Teoh, D Macintyre, PR Bennett, London UK

 
SESSION 8B BRITISH ASSOCIATION OF PERINATAL MEDICINE & NEONATAL SOCIETY  SESSION  
     
09.00 – 10.00 Free Papers  
     
8.7

Continuous EEG derived carbon dioxide monitor for newborn preterm babies – levels of agreement with partial pressure of arterial blood carbon dioxide

S Victor, C Jennings, C McKeering, A Buriro, P Gaydeki, Manchester UK

 
     
8.8

Neonatal Encephalopathy in the cooling therapy era – Preliminary cerebral magnetic resonance results from the MARBLE Consortium 

SS Pauliah,PJ Lally, A Bainbridge, DL Price, S Addison, FM Cowan, P Satodia, SC Wayte, A Soe, S Pattnayak, S Harigopal, LJ Abernethy, MA Turner, P Clarke, J Cheong, SN Basheer, A Alavi, S Shankaran, EB Cady, S Thayyil, London UK

 
     
8.9

Microstructural changes in neonatal encephalopathy revealed with  the neurite orientation dispertion and density imaging (NODDI) model

PJ Lally, H Zhang, SS Pauliah, DL Price, A Bainbridge, G Balraj, EB Cady, S Shankaran, S Thayyil, London UK 

 
     
8.10

Cranial ultrasound findings suggest that the injury pathway may begin many hours before delivery in encephalopathic infants in Uganda

CJ Tann, M Nakakeeto, C Hagmann, E Webb, N Nyombi, K Harvey-Jones, F Namiiro, K Burgoine, AM Elliott, JJ Kurinczuk, NJ Robertson, FM Cowan, London UK & Entebbe Uganda

 

 
     
10.00 – 10.30 The New NHS
Professor Allyson Pollock
Professor of Public Health Research and Policy, Queen Mary University of London
 
     
10.30 – 11.00 Coffee, Exhibition and Poster Viewing  
     
SESSION 9 SPECIAL GUEST LECTURES PLENARY
     
11.00 – 11.30 Assisted conception in women with serious pre-existing medical complications:  A bridge too far for maternal and perinatal mortality
Professor Scott Nelson, Muirhead Chair of Reproductive & Maternal Medicine
The University of Glasgow, Glasgow
 
     
11.30 – 12.00 Reconstructing congenital craniofacial malformations
Mr Simon Eccles, Consultant in Craniofacial Surgery, Chelsea and Westminster Hospital, London
 
     
12.00 – 12.30 Necrotizing enterocolitis
Professor Phillip Gordon
Associate Director of Neonatal Research for MEDNAX / Pediatrix, Florida, USA
 
     
12.30 – 13.30 Lunch, Exhibition and Poster Viewing  
     
SESSION 10 PLATFORM POSTERS PLENARY
     
13.30 – 14.00    
     
10.1

Can essential fatty acids prevent early preterm delivery? A meta-analysis of evidence

S Kar, S Thangaratinam, M Wong, E Rogozinska, London, UK

 
     
10.2

Association of the history of maternal-placental syndrome and cardiovascular disease in women with systemic lupus erythematosus

MC Soh, C Nelson-Piercy, F Dib, L McCowan, M Westgren, D Pasupathy, London, UK

 
     
10.3

Relative intakes of energy and protein in the first week after birth are associated with neurodevelopmental outcome at 24 months in extremely preterm infants

SHT Chan, MJ Johnson, AA Leaf, B Vollmer, Southampton, UK 

 
     
 10.4

Outcomes following the diagnosis of Hypoplastic Left Heart Syndrome: changes over a 15 year period.

L Peake, E Draper, D Field, Leicester, UK

 
     
10.5

Tissue engineering approach with acellular matrix supports affected diaphragm of an atrophic mouse model with activation of resident cells

De Coppi P, Urbani L, Piccoli M, Alvarez Fallas ME, Dedja A, Magrofuoco E, Elvassore N, Franzin C, Pozzobon M, London, UK 

 
     
10.6

Influence of prenatal adenovirus-VEGF gene therapy on mRNA expression of angiogenic related genes in fetal and postnatal ovine intestine

JS Caton, GQ Jia, JS Haring, RP Aitken, JS Milne, DJ Carr, AL David, JM Wallace, Fargo, USA

 
     
14.00 – 14.10 Session/Comfort break  
     
SESSION 11   PLENARY
     
14.10 – 14.55

The evolution of human adiposity                                                                             Professor Jonathan Wells, Professor of Anthropology and Paediatric Nutrition

Childhood Nutrition Research Centre, UCL Institute of Child Health, London

 
     
14.55 – 15.00 Presentation of Prizes  
     
SESSION 12 PROTECTING AND REPAIRING BRAINS PLENARY
     
15.00 – 15.30 Brain repair & stem cells (temporary title)
Professor Siddharthan Chandran
Professor of Neurology, University of Edinburgh
 
     
15.30 – 16.00 The role of maternally administered Magnesium Sulphate in the antenatal period for neuroprotection in the premature baby
Professor Stéphane Marret, Rouen, France
 
     
16.00 – 16.30

Protecting the newborn brain: new avenues
Professor Nikki Robertson, Professor of Perinatal Neuroscience, Neonatology, Institute for Women's Health, London

 
     
16.30 Close of Meeting